IACUC Learning Module - Xenopus aevis

IACUC Learning Module - Xenopus laevis

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Recommended Doses of Therapeutic Agents for Amphibians

Antibacterials/Antifungals

Drug Dose Dose Interval
Amikacin 5 mg/kg SC, IM IP q 24 hr
Benzalkonium chloride 0.25 mg/L
2 mg/L
Bath for 72 hr
Dip 1 hr, q 24 hr
Carbenicillin 200 mg/kg SC, IM, IP q 24 hr
Chloramphenicol 50 mg/kg
20 mg/L
SC, IM, IP q 24 hr
Bath
Enrofloxacin 5 mg/kg SC, IM, q 24 hr
Gentamicin 2.5-5 mg/kg
10 mg/L
SC, IM, IP q 24 hr
Bath
Ketoconazole 10 mg/kg PO q 24 hr
Mercurochrome 3 mg/L Bath for 72 hr
Methylene blue 4 mg/L Bath
Nalidixic acid 10 mg/L Bath
Nitrofurazone 10-20 mg/L Bath
Sodium chloride 4-6 gm/L Bath for 72 hr
Sulfamethazine 1 gm/L Bath
Oxytetracycline 50 mg/kg
25 mg/kg
1 gm/kg diet
PO q 12 hr
SC, IM q 24 hr
7 days
Trimethoprim/(sulfa) 3 mg/kg SC, PO q 24 hr

Antiparasitics

>
Drug Dose Dose Interval
Copper sulfate 500 mg/L Dip 2 min q 24 hr
Formalin 10% 1.5 ml/L Dip 10 min q 48 hr
Ivermectin 0.2-0.4 mg/kg Percutaneous
Levamisole 300 mg/L Bath for 24 hr
Metronidazole 150 mg/kg5 gm/kg diet PO repeat as needed
PO 5 days
Sodium Chloride 4-6 gm/L25 gm/L Bath Dip 10 min

Modified from Kirk's Current Therapy XI Small Animal Practice, edited by R.W. Kirk and J.D. Bonagura , publisher W.B. Saunders Co., 1992.


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