IACUC Learning Module - Surgery

IACUC Learning Module Surgery, Anesthesia - Vertebrate Species

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Laws & Regulations

Both the Animal Welfare Act and the Department of Health and Human Services have written, minimum "standards" for providing care before, during and after surgical procedures.

A project that involves more than momentary or slight pain or distress must involve the veterinarian, in the planning stage!

The Institutional Animal Care and Use Committee (IACUC) is responsible for supervising the use of animals at the institution and has authorized the attending veterinarian to oversee all surgical procedures. The veterinarian must have access to animals and ensure that daily observations of the animals are performed by qualified individuals. There must be routine inspections of sites where surgical procedures are conducted. The IACUC is required to stop any research project wherein non-compliance is suspected.

Animal Welfare Act

  • Passed in 1966

  • Protects against the theft of family dogs and cats, and includes virtually all warm blooded vertebrates

  • This act ensures that animals intended for use in research be provided humane care and treatment

  • USDA/APHIS (United States Department of Agriculture / Animal Plant Health Inspection Services)

  • Once a year USDA performs unannounced inspections of research institutions

  • They inspect housing areas, laboratories and offices where animals or records pertaining to animals are kept

  • They will also inspect surgery and post- operative records for compliance with their rules and regulations

  • Arizona Game and Fish

    GLP (Good Laboratory Practice)

  • Food and Drug Administration (FDA) requires the creations of Standard Operating Procedures (SOP) when you are planning a research project where findings will be reported to the FDA

  • The Surgery Section at UAC has developed SOPs that must be followed during a GLP study

  • Controlled Substance Act

  • Drugs which have the potential for addiction are classified under the law

  • Drug Enforcement Agency (DEA) enforces the law

  • Principle Investigator must obtain a DEA license to order and use controlled drugs

  • The Surgery Section is not allowed to sell you controlled drugs but can administer them for you. If you have a DEA license but are out of a drug, we can sell you one dose but you must provide us with a copy of your DEA license

  • IACUC (Institutional Animal Care and Use Committee)

  • They ensure that animals purchased for biomedical research are used and cared for in a responsible manner and that all legal guidelines are observed

  • Review protocols/amendments for approval

  • Surgery Section & IACUC:

  • Will review your protocol to make sure you are performing your surgeries in accordance to your protocol

  • Will make sure the animals that you are using are listed on your protocol

  • Ensure that you are using only the drugs listed on your protocol for the surgical procedure and post- operative care

  • Ensure that all personnel involved in the surgery are listed on your protocol and have taken the appropriate IACUC training courses

  • AAALAC (Association for Assessment and Accreditation of Laboratory Animal Care)


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    Certification Coordinator
    Last updated: 10/17/08