References

IACUC Learning Module - Dogs

PreviousPrevious PageNext PageNext

References

Allen, P.L., Dogs in Research: Biology, Husbandry, Diseases and as a Model, Research Animal Methods, October 1994.

Crow SE, Walshaw SO (Morton CB - illustrator): Manual of Clinical Procedures in the Dog and Cat. J.B. Lippincott Company, Philadelphia, 1987. pp. 5 - 9, 19, 36-39, 64-67, 145.

Lewis SM, Carraway JH: Large Animal Models of Human Disease. Lab Animal. January 1992. pp. 22 - 25

Sonsthagen TF: Restraint of Domestic Animals. American Veterinary Publications, Inc., Goleta California, 1991. pp. 31-37.

Animal Care Specialist School, Walter Reed Army Institute of Research: Small Animal Restraint. Course instruction manual. Walter Reed Army Institute of Research, Washington, D.C.

Assistant Lab Animal Technician Training Manual Series, Vol 1, AALAS. Edited by Dennis Stark, DVM, PhD, and Marshall E. Ostrou M.S. C, 1989, AALAS

Prepared by Jane Criswell, Patt Allen and Grace Aranda, 1996.

Doses of Preanesthetic Drugs for Laboratory Species

(All doses are in mg/kg unless otherwise noted)

Drug Route Ferret Cat Dog
Atropine SC - .05 .05
Glycopyrollate SC,IM - .01 .01
Acepromazine Varied .2 IM .1 - .2 IM .1 - .2 IM
Diazepam (Valium) Varied 2 IM .1 IV not alone .1 IV not alone
Midazolam (Versed) Varied - - -
Xylazine Varied 1 SC, IM 1-2 IM,SC 1-2 IM,SC
Metdetomidine Varied -50-150 Fg/kg
SC,IM
40-100 Fg/kg
IV,IM
Ketamine Varied 30-60 IM 6-20 IM -
Tiletaminezolazepam
(Telazol)
IM - 1-31-3
Morphine IM - - 1-2 IM
Fentanyl/Droperidol
(Innovar-Vet)
IM - - .13

Anesthetic Induction Drugs

Drug Route Ferret Cat Dog
Pentobarbital IV,IP 25-30 25 25-30
Thiopental IV - 10-20 10-15
Methohexital IV - 4-8 4-8
Propofol IV - 4-8 4-8
Etomidate IV - 1-2 after premed 1-2 after premed
Ketamine/Acepromazine IM 25/.25 - -
Ketamine/Xylazine IM,IV,IP 25/2 7/1 7/1
Ketamine/Diazepam IM,IV,IP 25/2 - -
Ketamine/Metdetomidine IP,IM,IV 8/0.1 IM 7+40-80 Fg IM 5+40 Fg IM
Tiletamine/Telazol IM 22 IM 1-3 IM 1-3 IM
Chloralose IV - 80-90 80-110
Urethane IV,IP - 1000 IV 1000 IV

IM - IntramuscularIP - IntraperitonealPO - Oral
SC - SubcutaneousIV - Intravenous* - Variable effect

From the Anesthesia & Chemical Restraint Reference

Dosages for Nonsteroidal Anti-Inflammatory Drugs and Sedative Analgesics for Pain Management (mg/kg)

DrugFerret Cat Dog
NSAIDS
Acetaminophen NA DO NOT USE 15 TID PO
Aspirin NA 10 PO every 48-72
hrs
10 PO TID
Carprofen - 4 SC,IV 4 IV,SC
1-2 PO BID
Flunixin NA NA 1 IM
DO NOT REPEAT
Ibuprofen NA 10 PO every
1-2 days
NA
Indomethacin - - -
Ketaprofen - 2 IM,IV,SC sid
1 PO
1 IM,IV,SC sid
1 PO
Piroxocam - - -
Phenylbutazone NA NA 9 PO TID
Sedative-Analgesics
Xylazine 1 IM 1 IM 1 IM
Detomidine NA NA NA
Medetomidine NA NA .01-.04 IM

IM - IntramuscularIP - IntraperitonealPO - Oral
SC - SubcutaneousIV - Intravenous* - Variable effect

From the Anesthesia & Chemical Restraint Reference

Dosages for Opiate Analgesics (mg/kg)

DrugFerret Cat Dog
Buprenorphine 0.01-0.03
IV,IM,SC
8-12 H
0.005-0.01
IM
8-12H
0.01-0.2
SC,IM
12H
Butorphanol 0.4
IM
4-6H
0.4
SC
3-6H
0.4-0.8
SC
3-6H
Fentanyl NA NA 0.04-0.8
IM,IV
1-2H
Meperidine NA 10
SC,IM
2-3H
10
SC,IM
2-3H
Morphine NA 0.1
SC
4-8H
0.5-1
IM,SC
4-6H
Nalbuphine NA 1.5-3
SC
3-4H
0.5-2
SC
3-4H
Oxymorphone NA 0.2
IM,SC
4-6H
0.2
IM,SC
4-6H
Pentazocine NA 2-3
IM
4H
2-3
IM
4H
IM - IntramuscularIP - IntraperitonealPO - Oral
SC - SubcutaneousIV - Intravenous* - Variable effect

From the Anesthesia & Chemical Restraint Reference


Previous PagePrevious PageNext PageNext Page
Back to Table of Contents Back to Table of Contents

Back to Training Modules Training Modules


This web page is maintained by Certification Coordinator
 
Last updated: 01/02/2008 gea

bar2.gif (1779 bytes)