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The University of Arizona Institutional Animal Care and Use Committee Handbook
INTRODUCTION
I.
INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE: RESPONSIBILITIES, MEMBERSHIP, AND AUTHORITY
A. INVOLUNTARY REGULATIONS
- 1. Animal Welfare Act
-
a. Summary of the Act
- b. The IACUC and the ACT
- 2. Public Health Service Policy
-
a. Institutional Program
- b. Institutional Status
- c. IACUC
- d. Investigator
- e. Institution
- f. PHS Policy
- 3. Good Laboratory Practices Act
- 4. Private Funding Agencies
B. VOLUNTARY
- 1. Association for the Assessment and Accreditation of Laboratory Animal Care International (AAALAC)
- 2. Institutional or Individual IACUC Requirements
- 3. Individual Users
C. SUMMARY
II. THE UNIVERSITY OF ARIZONA INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE:ROLES AND RESPONSIBILITIES
-
A. Membership
- B. Authority
- C. Responsibilities
- D. Meetings
- E. General
III. ROLE OF THE IACUC COMMUNITY MEMBERS
-
A. Roles of Community Members
- B. Desirable Traits for the Lay Committee Member
IV. PAIN
-
A. Pain and Distress: Definitions
- B. Analgesics and Anesthesia: Definitions
- C. Signs of Pain
- D. Signs of Acute Pain
- E. Signs of Chronic Pain
- F. Species Specific Signs
- 1. Primates
- 2. Horses
- 3. Cattle
- 4. Sheep and Goats
- 5. Pigs
-
6. Dogs
- 7. Cats
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8. Rabbits
- 9. Rodents
- 10. Birds
- 11. Fish
V. SPECIAL POLICIES OF THE UNIVERSITY OF ARIZONA INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE
- A. Euthanasia as an Alternative to Death as an Endpoint in Rodents
- B. Euthanasia by Cervical Dislocation or Decapitation
- 1. Cervical Dislocation
- 2. Decapitation
- 3. Scientific Justification
- C. Immunization of Research Animals for Antibody Production
- 1. Freund's Adjuvant
- 2. Footpad Injections
- 3. Post-Injection Care
- 4. Ascites Production
- D. Investigation of Concerns Involving the Care and Use of Animals
- 1. Regulatory Authority
- 2. University of Arizona IACUC Policy
- a. IACUC
- b. Steps in the Process
- c. IACUC Review
- d. IACUC Investigation of Alleged Violations
- 3. Confidentiality of the Complainant
- a. Regulatory Authority: AWA Section 2.32(c)(4)
- b. IACUC Policy
- 4. Authority of the Attending Veterinarian
- a. Regulatory Authority: AWA Section 2.33(as)(2)
- b. IACUC Policy
- 5. Suspension of Animal Activities
- a. Regulatory Authority: AWA Section2.31(d)(xi)(6) and (7)
- b. IACUC Policy
- E. LD50 Testing
- 1. Definitions
- 2. IACUC Policy
- 3. Additional Notes
- F. Q Fever
- 1. Synonyms
-
2. Agent Coxiella burnetii
- 3. Mode of Transportation
- 4. The disease in Man
-
5. Control
-
6. IACUC Policy
- 7. Statement of Compliance
- G. Satellite Animal Facilities
- H. Self Insurance Plan
- I. Training
VI. PROTOCOL REVIEW PROCESS
- Protocol Flow Chart
-
A. Accelerated Review
- B. Full Review
- Definition of Terms
ANIMAL PROTOCOL REVIEW
FORM (link to forms page)
CERVICAL
DISLOCATION OR DECAPITATION AUTHORIZATION MEMO
Q FEVER POLICY
FOR THE UNIVERSITY OF ARIZONA
APPLICATION
FOR COMPENSATION FOR ANIMAL LOSS DUE TO INFECTIOUS ORGANISMS
DESCRIPTION OF THE ANIMAL CARE
AND USE PROGRAM - for submission to granting agencies
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Guide for the Care and Use of Laboratory Animals
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University Animal Care
03/05/2008